Reply: ovarian reserve screening: a scientific and ethical analysis.
نویسندگان
چکیده
age at menopause using serum concentration of anti-mullerian hormone. J Clin Endocrinol Metab 2013;98:729–735. Titus S, Li F, Stobezki R, Akula K, Unsal E, Jeong K, Dickler M, Robson M, Moy F, Goswami S et al. Impairment of BRCA1-related DNA doublestrand break repair leads to ovarian aging in mice and humans. Sci Transl Med 2013;5:172ra21. Tremellen K, Savulescu J. Ovarian reserve screening: a scientific and ethical analysis. Hum Reprod 2014;29:2606–2614. vanDorpW, van denHeuvel-EibrinkMM, de Vries AC, Pluijm SM, Visser JA, Pieters R, Laven JS.Decreased serumanti-Mullerian hormone levels in girls with newly diagnosed cancer. Hum Reprod 2014;29:337–342.
منابع مشابه
Ovarian reserve screening: a scientific and ethical analysis.
Ovarian reserve (OR) screening of the general population is generally not advocated as it has not been conclusively established to reflect immediate potential for natural conception, while it may also potentially create anxiety for women. However, in this paper, we argue in support of screening of the general population for diminished OR. First, OR tests such as measurements of anti-Müllerian h...
متن کاملP-201: Relation between AMH Levels and Ovarian Response in ART Cycles
Background: Ovarian reserve and ovarian response both are of the most important key factors in infertility treatment. Anti mullerian hormone (AMH) is one of lab tests that can predict ovarian reserve. relation between this assay and ovarian response can guide physition to choose the best protocol for the worst reserve. Materials and Methods: In a prospective cohort study, 110 infertile women (2...
متن کاملP-203: Examination of FMR1 Gene Transcription and Protein Expression in Patients with Diminished Ovarian Reserve Reffered to Royan institute
Background: Diminished ovarian reserve (DOR) is a primary infertility disorder characterized by a reduction in the number and/or quality of oocytes, usually accompanied by high follicle-stimulating hormone (FSH) levels and regular menses. DOR aetiology factors are different, such as genetic factors, ageing, autoimmune disorders, adrenal gland impairment factors and iatrogenic causes, e.g. chemo...
متن کاملP-204: Evaluation of FMR1 Gene Regulatory Region for The Epigenetic Mark of H3K9 Acetylation in Blood Cells of Patients with Diminished Ovarian Reserve Reffered to Royan Institute
Background: Diminished ovarian reserve (DOR) is a heterogeneous disorder causing infertility, characterized by a decreased number of oocytes and high FSH level, the genetic cause of which is still unknown. The association between FMR1 premutations(50-200 CGG repeats) and the premature ovarian failure( POF) disease has suggested that FMR1 gene acts as a risk factor for POF and recently for DOR p...
متن کاملLETTERS TO THE EDITOR Ovarian reserve screening: a scientific and ethical analysis
Sir, In a recent article, Tremellen and Savulescu (2014) ‘argue in support of screening the general population for diminished ovarian reserve (OR)’. They state that OR ‘is determined by the net result of the initial size of the primordial follicle endowment, the natural rate of atretic loss and the impact of any insult that may hasten follicle depletion’. However, OR is not defined, nor do they...
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ورودعنوان ژورنال:
- Human reproduction
دوره 30 4 شماره
صفحات -
تاریخ انتشار 2015